Wholly proprietary versus wholly open knowledge strategies: Some empirical evidences from Italian biotech firms

This paper focuses on biotechnologies and biotech companies. Our aim is to develop a model for assessing the openness degree of knowledge governance strategies, applying it to the biotech firms. Biotech production is described as an emerging meta-industry in the global economy, fostering through new products, many socio-economic fields. Its main features are: a close relationship among knowledge, innovation and competitiveness; the need for collaborative research; the importance of small firms. Our paper begins with a brief characterization of the biotech meta-sector. We then review the literature regarding the advantages and disadvantages of ‘‘wholly proprietary’’ versus ‘‘wholly open’’ knowledge strategies. Next we propose a model and report the main results of its application to biotech companies in Italy. In conclusion, we evaluate the degree of openness of the company knowledge strategies based upon empirical evidence from our research in the field.