High-performance liquid chromatography utilizing chiral stationary phases (CSPs) is well established as a very simple and efficient method for obtaining discrete amounts of optically active compounds with high e.e., as well as for determining their enantiomeric composition We wish to demonstrate in the present work that a totally synthetic brush-type π-acidic CSP based on a bis(N,N′-3,5-dinitrobenzoyl) derivative of (R,R)- or (S,S)-trans-1,2-diaminocyclohexane as selector can be used successfully to resolve variety of chiral organophosphorus compounds containing stereogenic centers at phosphorus
Direct chromatographic resolution of P-chiral organophosphorous compounds at analytical and preparative levels / Gasparrini, Francesco; F., Maggio; Villani, Claudio; A., Brandi; S., Cicchi; K. M., Pietrusiewicz; M., Koprowski. - In: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS. - ISSN 1042-6507. - STAMPA. - 111:(1996), pp. 653-653. [10.1080/10426509608054650]
Direct chromatographic resolution of P-chiral organophosphorous compounds at analytical and preparative levels
GASPARRINI, Francesco;VILLANI, Claudio;
1996
Abstract
High-performance liquid chromatography utilizing chiral stationary phases (CSPs) is well established as a very simple and efficient method for obtaining discrete amounts of optically active compounds with high e.e., as well as for determining their enantiomeric composition We wish to demonstrate in the present work that a totally synthetic brush-type π-acidic CSP based on a bis(N,N′-3,5-dinitrobenzoyl) derivative of (R,R)- or (S,S)-trans-1,2-diaminocyclohexane as selector can be used successfully to resolve variety of chiral organophosphorus compounds containing stereogenic centers at phosphorusI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
