The use of enoxaparin as a replacement drug to standard heparin, for anticoagulation during extracorporeal circulation, in patients with heparin-induced thrombocytopenia, is still very limited. Enoxaparin significantly reduces thrombin formation and activity during cardiopulmonary bypass. The prolonged circulating rate, slow elimination rate and non-total reversion of enoxaparin by protamine can induce important postoperative bleeding. We are describing the first case of cardiac transplantation where enoxaparin was used as a replacement drug to standard heparin. (C) 2000 Elsevier Science B.V. All rights reserved.
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Titolo: | Undergoing cardiopulmonary bypass using enoxaparin only during a cardiac transplantation procedure |
Autori: | |
Data di pubblicazione: | 2000 |
Rivista: | |
Handle: | http://hdl.handle.net/11573/39860 |
Appartiene alla tipologia: | 01a Articolo in rivista |