We propose a structural model of Candida cylindracea lipase (CCL) based on the reported X-ray structure of the highly homologous Geotrichum candidum lipase (GCL). The network of interactions around the active site, the salt and disulfide bridge pattern is conserved in the proposed structure. Functional, structural and evolutionary aspects of the peculiar usage of CTG codons by C. cylindracea ATCC 14830 are discussed. © 1992.

Homology-derived three-dimensional structure prediction of Candida cylindracea lipase / Sonia, Longhi; Marina, Lotti; Fabrizia, Fusetti; Elisabetta, Pizzi; Tramontano, Anna; Lilia, Alberghina. - In: BIOCHIMICA ET BIOPHYSICA ACTA. L, LIPIDS AND LIPID METABOLISM. - ISSN 0005-2760. - 1165:1(1992), pp. 129-133. [10.1016/0005-2760(92)90084-9]

Homology-derived three-dimensional structure prediction of Candida cylindracea lipase

TRAMONTANO, ANNA;
1992

Abstract

We propose a structural model of Candida cylindracea lipase (CCL) based on the reported X-ray structure of the highly homologous Geotrichum candidum lipase (GCL). The network of interactions around the active site, the salt and disulfide bridge pattern is conserved in the proposed structure. Functional, structural and evolutionary aspects of the peculiar usage of CTG codons by C. cylindracea ATCC 14830 are discussed. © 1992.
1992
(c. cylindracea); biological evolution; candida; chemistry/metabolism; enzyme structure; enzymology; fungal lipase; genetic code; lipase; model-building; models; molecular; nonuniversal; x-ray diffraction; yeast
01 Pubblicazione su rivista::01a Articolo in rivista
Homology-derived three-dimensional structure prediction of Candida cylindracea lipase / Sonia, Longhi; Marina, Lotti; Fabrizia, Fusetti; Elisabetta, Pizzi; Tramontano, Anna; Lilia, Alberghina. - In: BIOCHIMICA ET BIOPHYSICA ACTA. L, LIPIDS AND LIPID METABOLISM. - ISSN 0005-2760. - 1165:1(1992), pp. 129-133. [10.1016/0005-2760(92)90084-9]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/398327
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 10
social impact