Circular dichroism and structure of Schiff's bases of hydroxybenzaldehydes anchored to poly(L-lysine) and poly(L-α,γ-diaminobutyric acid).

Schiff's bases of ortho-, meta- and para-hydroxybenzaldehydes with poly(l-α,γ-diaminobutyric acid) and poly(l-lysine) were investigated in solution of methanol and methanol-water mixtures by circular dichtroism, absorption spectroscopy and equilibrium dialysis techniques. The results so far obtained allow us to propose a molecular model, which fully justifies the stereospecific binding of ortho-hydroxybenzaldehyde with the polypeptide chain; moreover it is able to explain the dramatic change of the chemical equilibrium in the hydrolysis reaction.