IS UNRELATED LIVING DONOR A VALID ORGAN SOURCE IN RENAL TRANSPLANTATION UNDER CyA THERAPY?

Though there are several advantages to using liver donors in kidney transplantation, the foremost effort is to improve the persistent shortage of cadaveric d o n o r s . 1 2 Nevertheless, the use of living unrelated donors (LURDs) remains controversial, even though under cyclosporine (CyA) regimen, on the theoretical basis that the functional survival rates for grafts transplanted between zero haplotype pairs would be lower than those of one haplotype matched pairs.1 Following our previous studies on living donors,4 ''* our entire experience is reported here in order to evaluate whether grafts matched for one or zero haplotypes with LURDs are as successful as transplantation in recipients of well H L A matched sibling kidneys (LRD). In addition the analysis has been performed according to the immunosuppression protocol used in the recipient