A 67-year-old white man with esophageal adenocarcinoma presented with Peutz-Jeghers-like macules on the lips, face, nipples, and rectal mucosa. Pathological examination of the macules showed atypical melanocytes in the epidermis. The pleomorphic large melanocytes resembled the neoplastic cells seen in melanoma in situ. This is the first report of proliferation of atypical melanocytes in Peutz-Jeghers-like melanosis associated with a primary esophageal adenocarcinoma.
PEUTZ-JEGHERS-LIKE MELANOTIC MACULES ASSOCIATED WITH ESOPHAGEAL ADENOCARCINOMA / Ana, Eng; Ali, Armin; Mary, Massa; Gradini, Roberto. - In: AMERICAN JOURNAL OF DERMATOPATHOLOGY. - ISSN 0193-1091. - STAMPA. - 13:2(1991), pp. 152-157. [10.1097/00000372-199104000-00008]
PEUTZ-JEGHERS-LIKE MELANOTIC MACULES ASSOCIATED WITH ESOPHAGEAL ADENOCARCINOMA
GRADINI, Roberto
1991
Abstract
A 67-year-old white man with esophageal adenocarcinoma presented with Peutz-Jeghers-like macules on the lips, face, nipples, and rectal mucosa. Pathological examination of the macules showed atypical melanocytes in the epidermis. The pleomorphic large melanocytes resembled the neoplastic cells seen in melanoma in situ. This is the first report of proliferation of atypical melanocytes in Peutz-Jeghers-like melanosis associated with a primary esophageal adenocarcinoma.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
