Purpose: To evaluate the ability of MRI to identify intra and extraintestinal findings of celiac disease in an adult population. Materials and Methods: Forty-one subjects (18 men and 23 women: mean age = 41.3 years; 31 with biopsy-proven celiac disease. and 10 healthy volunteers) underwent MRI of the small bowel. MR studies were performed on a 1.5-T magnet using T2-weighted half-Fourier single-shot turbo spin-echo (HASTE) and true fast imaging in steady-state precession (True-FISP) sequences. The MR features and sensitivity,. and the specificity and accuracy of some of these features are described. Results: In the 31 celiac patients, MRI showed bowel dilatation in 61.3% (N = 19), increased number of ileal folds in 48.4% (N = 15), reversed fold pattern abnormality in 38.7% (N = 12), increased wall thickness in 16.1% (N = 5), duodenal stenosis in 6.5% (N = 2), intussusception in 12.9% (N = 4). mesenteric lymphadenopathy in 41.9% (N = 13), mesenteric vascular changes in 22.6% (N = 7), ascites in 6.5% (N = 2). and no abnormalities in 12.9% (N = 4). The volunteers had unremarkable exams. The overall specificity and accuracy were 100%, and sensitivity was 79% and 75% for increased number of ileal folders and reversed fold pattern abnormality. respectively. Conclusion: MRI is able to demonstrate intra- and extraintestinal features that may lead to the diagnosis of celiac disease in adults.
Adult celiac disease: What is the role of MRI? / Tomei, Ernesto; Richard C., Semelka; Larissa, Braga; Laghi, Andrea; Paolantonio, Pasquale; Mario, Marini; Passariello, Roberto; M. D., Tola; Luigi, Sabbatella; Picarelli, Antonio. - In: JOURNAL OF MAGNETIC RESONANCE IMAGING. - ISSN 1053-1807. - STAMPA. - 24:3(2006), pp. 625-629. [10.1002/jmri.20664]
Adult celiac disease: What is the role of MRI?
TOMEI, Ernesto;LAGHI, ANDREA;PAOLANTONIO, PASQUALE;PASSARIELLO, Roberto;PICARELLI, Antonio
2006
Abstract
Purpose: To evaluate the ability of MRI to identify intra and extraintestinal findings of celiac disease in an adult population. Materials and Methods: Forty-one subjects (18 men and 23 women: mean age = 41.3 years; 31 with biopsy-proven celiac disease. and 10 healthy volunteers) underwent MRI of the small bowel. MR studies were performed on a 1.5-T magnet using T2-weighted half-Fourier single-shot turbo spin-echo (HASTE) and true fast imaging in steady-state precession (True-FISP) sequences. The MR features and sensitivity,. and the specificity and accuracy of some of these features are described. Results: In the 31 celiac patients, MRI showed bowel dilatation in 61.3% (N = 19), increased number of ileal folds in 48.4% (N = 15), reversed fold pattern abnormality in 38.7% (N = 12), increased wall thickness in 16.1% (N = 5), duodenal stenosis in 6.5% (N = 2), intussusception in 12.9% (N = 4). mesenteric lymphadenopathy in 41.9% (N = 13), mesenteric vascular changes in 22.6% (N = 7), ascites in 6.5% (N = 2). and no abnormalities in 12.9% (N = 4). The volunteers had unremarkable exams. The overall specificity and accuracy were 100%, and sensitivity was 79% and 75% for increased number of ileal folders and reversed fold pattern abnormality. respectively. Conclusion: MRI is able to demonstrate intra- and extraintestinal features that may lead to the diagnosis of celiac disease in adults.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.