Essential hypertension is characterized by increased peripheral vascular resistance to blood flow. The endothelium is a crucial regulator of vascular tone. Its function is impaired in patients with hypertension, with reduced vasodilation, increased vascular tone associated with a proinflammatory and prothrombotic state. Low-grade inflammation localized in vascular tissue is therefore recognized as an important contributor to the pathophysiology of hypertension, to the initiation and progression of atherosclerosis as well as to the development of cardiovascular diseases. © 2011 Carmine Savoia et al.

Vascular inflammation and endothelial dysfunction in experimental hypertension / Savoia, Carmine; Lidia, Sada; Luigi, Zezza; Lorenzo, Pucci; Francesco Maria, Lauri; Alberto, Befani; Alonzo, Alessandro; Volpe, Massimo. - In: INTERNATIONAL JOURNAL OF HYPERTENSION. - ISSN 2090-0384. - 2011:(2011), pp. 1-8. [10.4061/2011/281240]

Vascular inflammation and endothelial dysfunction in experimental hypertension

SAVOIA, Carmine;ALONZO, ALESSANDRO;VOLPE, Massimo
2011

Abstract

Essential hypertension is characterized by increased peripheral vascular resistance to blood flow. The endothelium is a crucial regulator of vascular tone. Its function is impaired in patients with hypertension, with reduced vasodilation, increased vascular tone associated with a proinflammatory and prothrombotic state. Low-grade inflammation localized in vascular tissue is therefore recognized as an important contributor to the pathophysiology of hypertension, to the initiation and progression of atherosclerosis as well as to the development of cardiovascular diseases. © 2011 Carmine Savoia et al.
2011
01 Pubblicazione su rivista::01a Articolo in rivista
Vascular inflammation and endothelial dysfunction in experimental hypertension / Savoia, Carmine; Lidia, Sada; Luigi, Zezza; Lorenzo, Pucci; Francesco Maria, Lauri; Alberto, Befani; Alonzo, Alessandro; Volpe, Massimo. - In: INTERNATIONAL JOURNAL OF HYPERTENSION. - ISSN 2090-0384. - 2011:(2011), pp. 1-8. [10.4061/2011/281240]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/386886
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