We present two cases of advanced ovarian cancer treated with neoadjuvant chemotherapy with standard tri-weekly carboplatin and paclitaxel. Therapy was converted to weekly regimens because of disease progression, resulting in disease response. Weekly regimens could overcome drug resistance and this strategy should be attempted before abandoning first-line chemotherapy in favor of palliation.
Thinking twice before abandoning first-line chemotherapy in ovarian cancer: report of two cases and literature review. Passing from tri-weekly to weekly regimens / Marchetti, Claudia; Bellati, Filippo; Musella, Angela; Napoletano, Chiara; DI DONATO, Violante; Sandro, Pignata; Nuti, Marianna; BENEDETTI PANICI, Pierluigi; Perniola, Giorgia. - In: INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY. - ISSN 1341-9625. - STAMPA. - 17:4(2012), pp. 385-389. [10.1007/s10147-011-0300-9]
Thinking twice before abandoning first-line chemotherapy in ovarian cancer: report of two cases and literature review. Passing from tri-weekly to weekly regimens
MARCHETTI, CLAUDIA;BELLATI, FILIPPO;MUSELLA, ANGELA;NAPOLETANO, Chiara;DI DONATO, VIOLANTE;NUTI, Marianna;BENEDETTI PANICI, PIERLUIGI;PERNIOLA, GIORGIA
2012
Abstract
We present two cases of advanced ovarian cancer treated with neoadjuvant chemotherapy with standard tri-weekly carboplatin and paclitaxel. Therapy was converted to weekly regimens because of disease progression, resulting in disease response. Weekly regimens could overcome drug resistance and this strategy should be attempted before abandoning first-line chemotherapy in favor of palliation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
