Tourette syndrome (TS) is hypothesised to be caused by an abnormal organization of movement control. The aim of this study was to use functional magnetic resonance imaging to study motor cortex activation in a TS patient. Usual and unusual self-paced voluntary movements were performed. The TS patient displayed supplementary motor area (SMA) activation during both tasks. This activation reflects a continuous use of the SMA to perform the voluntary motor movements required in both tasks. Moreover, the absence of tics during the execution of these voluntary motor tasks suggests that tic activity may be suppressed by additional mental effort. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
Gilles de la Tourette syndrome and voluntary movement: A functional MRI study / Fattapposta, Francesco; Rita, Restuccia; Colonnese, Claudio; Ludovica, Labruna; Girolamo, Garreffa; Bianco, Federico. - In: PSYCHIATRY RESEARCH. NEUROIMAGING. - ISSN 0925-4927. - 138:3(2005), pp. 269-272. [10.1016/j.pscychresns.2005.02.001]
Gilles de la Tourette syndrome and voluntary movement: A functional MRI study
FATTAPPOSTA, FRANCESCO;COLONNESE, Claudio;BIANCO, Federico
2005
Abstract
Tourette syndrome (TS) is hypothesised to be caused by an abnormal organization of movement control. The aim of this study was to use functional magnetic resonance imaging to study motor cortex activation in a TS patient. Usual and unusual self-paced voluntary movements were performed. The TS patient displayed supplementary motor area (SMA) activation during both tasks. This activation reflects a continuous use of the SMA to perform the voluntary motor movements required in both tasks. Moreover, the absence of tics during the execution of these voluntary motor tasks suggests that tic activity may be suppressed by additional mental effort. (c) 2005 Elsevier Ireland Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.