Ischemic stroke in young patients is a relatively rare event. Few studies have examined the long-term prognosis. The aim of this study was to evaluate the long-term outcome to identify clinical, laboratory and radiologic patterns as possible predictors for mortality, recurrence and functional recovery. We prospectively evaluated 94 patients (42 males and 52 females, aged 14-45 years, mean age 35.5 years, SD 8.4) admitted to our Neurological Department, for first acute ischemic stroke. A 48-month follow-up was performed. The patients were classified according to TOAST and Baltimore classification and Bamford criteria. The severity of the neurological deficit on admission was assessed using the NIHSS. The follow-up included a clinical visit, the modified Ranking scale (mRs) score, Barthel index (BI), and magnetic resonance imaging and intra-extracranial vessel Angio MRI. A good functional outcome (mRS 0-1) was found in 74 patients and unfavourable outcome (mRS 2-6) in 20 patients. 16 patients had a recurrent cerebral ischemic event: 5 patients had stroke and 11 patients had TIA. The average incidence annual rate of recurrence was 4.5% and a mortality rate was of 1.06%. Our study does not demonstrate any predictive factor related to clinical outcome. The relevant data of neuroradiological follow-up is the presence of clinically silent lesions in nine patients, considered as a recurrent stroke. To attribute a prognostic role to these lesions, clinical and neuroradiological follow-up needs to be continued.

Cerebral ischemia in young patients (under 45 years of age): clinical and neuroradiological follow-up / Patella, Rosalba; Alessandra, Spalloni; Marco, Ferrari; LA STARZA, Sara; Bozzao, Alessandro; Rasura, Maurizia. - In: NEUROLOGICAL SCIENCES. - ISSN 1590-1874. - STAMPA. - 32:3(2011), pp. 427-432. [10.1007/s10072-011-0507-6]

Cerebral ischemia in young patients (under 45 years of age): clinical and neuroradiological follow-up.

PATELLA, ROSALBA;LA STARZA, SARA;BOZZAO, ALESSANDRO;RASURA, Maurizia
2011

Abstract

Ischemic stroke in young patients is a relatively rare event. Few studies have examined the long-term prognosis. The aim of this study was to evaluate the long-term outcome to identify clinical, laboratory and radiologic patterns as possible predictors for mortality, recurrence and functional recovery. We prospectively evaluated 94 patients (42 males and 52 females, aged 14-45 years, mean age 35.5 years, SD 8.4) admitted to our Neurological Department, for first acute ischemic stroke. A 48-month follow-up was performed. The patients were classified according to TOAST and Baltimore classification and Bamford criteria. The severity of the neurological deficit on admission was assessed using the NIHSS. The follow-up included a clinical visit, the modified Ranking scale (mRs) score, Barthel index (BI), and magnetic resonance imaging and intra-extracranial vessel Angio MRI. A good functional outcome (mRS 0-1) was found in 74 patients and unfavourable outcome (mRS 2-6) in 20 patients. 16 patients had a recurrent cerebral ischemic event: 5 patients had stroke and 11 patients had TIA. The average incidence annual rate of recurrence was 4.5% and a mortality rate was of 1.06%. Our study does not demonstrate any predictive factor related to clinical outcome. The relevant data of neuroradiological follow-up is the presence of clinically silent lesions in nine patients, considered as a recurrent stroke. To attribute a prognostic role to these lesions, clinical and neuroradiological follow-up needs to be continued.
2011
follow-up; stroke; silent cerebral lesions; young
01 Pubblicazione su rivista::01a Articolo in rivista
Cerebral ischemia in young patients (under 45 years of age): clinical and neuroradiological follow-up / Patella, Rosalba; Alessandra, Spalloni; Marco, Ferrari; LA STARZA, Sara; Bozzao, Alessandro; Rasura, Maurizia. - In: NEUROLOGICAL SCIENCES. - ISSN 1590-1874. - STAMPA. - 32:3(2011), pp. 427-432. [10.1007/s10072-011-0507-6]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/381948
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