We investigated the patterns of chronic hepatitis B virus (HBV)-related disease in a large cohort of HBsAg-positive patients, in Central Italy, by collecting a screening form with demographic, clinical and laboratory data. Overall, 737 HBsAg-positive cases were included (70% male; median age 52 years): 30% were inactive HBsAg carriers, 51% had chronic hepatitis B (CHB) and 19% had HBV-related cirrhosis. Patients from non-European Union (EU) countries (n = 65) were significantly younger, had a higher prevalence of HBeAg-positive infection and hepatitis delta virus (HDV) co-infection than patients of Italian origin. Therefore, as immigration from non-EU countries continues to grow, we can expect a change in the landscape of HBV-related disease in our area.
Patterns of chronic hepatitis B in Central Italy: a cross-sectional study / P., P., I., L., C., T., D., D.P., F., B., L., D.M., O., S., G., R., G. L., R., L., N., M., R., DE SANTIS, A., Levrero, M., G., A., M. A., L., B. E., A., M., A., Furlan, C., For The Hep B., F.N.I.. - In: EUROPEAN JOURNAL OF PUBLIC HEALTH. - ISSN 1101-1262. - STAMPA. - 20:6(2010), pp. 711-713. [10.1093/eurpub/ckp168]
Patterns of chronic hepatitis B in Central Italy: a cross-sectional study
DE SANTIS, Adriano;LEVRERO, Massimo;FURLAN, Caterina;
2010
Abstract
We investigated the patterns of chronic hepatitis B virus (HBV)-related disease in a large cohort of HBsAg-positive patients, in Central Italy, by collecting a screening form with demographic, clinical and laboratory data. Overall, 737 HBsAg-positive cases were included (70% male; median age 52 years): 30% were inactive HBsAg carriers, 51% had chronic hepatitis B (CHB) and 19% had HBV-related cirrhosis. Patients from non-European Union (EU) countries (n = 65) were significantly younger, had a higher prevalence of HBeAg-positive infection and hepatitis delta virus (HDV) co-infection than patients of Italian origin. Therefore, as immigration from non-EU countries continues to grow, we can expect a change in the landscape of HBV-related disease in our area.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
