Devices used for biological experiments on cell cultures can present a low impedance. In this paper, a numerical and experimental characterization of a high-voltage, nanosecond-pulse, 10-Omega generator is proposed. The generator makes use of a combination of microstrip-line technology and laser-triggered photoconductive semiconductor switches that operate in the linear regime. A standard electroporation cuvette is used to load the generator. SPICE and finite-difference time-domain (FDTD) models of the whole setup (i.e., the generator and the cuvette) are developed. Numerical characterization is performed comparing SPICE analysis and FDTD simulations. Experimental characterization on a built prototype is carried out by means of a wideband frequency voltage sensor. A good level of consistency is obtained between the numerical and the experimental voltage intensities measured across the cuvette electrodes.
A 10-Omega High-Voltage Nanosecond Pulse Generator / Caterina, Merla; S., El Amari; M., Kenaan; Liberti, Micaela; Apollonio, Francesca; D., Arnaud Cormos; V., Couderc; P., Leveque. - In: IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES. - ISSN 0018-9480. - STAMPA. - 58:12 PART 2(2010), pp. 4079-4085. [10.1109/tmtt.2010.2086470]
A 10-Omega High-Voltage Nanosecond Pulse Generator
LIBERTI, Micaela;APOLLONIO, Francesca;
2010
Abstract
Devices used for biological experiments on cell cultures can present a low impedance. In this paper, a numerical and experimental characterization of a high-voltage, nanosecond-pulse, 10-Omega generator is proposed. The generator makes use of a combination of microstrip-line technology and laser-triggered photoconductive semiconductor switches that operate in the linear regime. A standard electroporation cuvette is used to load the generator. SPICE and finite-difference time-domain (FDTD) models of the whole setup (i.e., the generator and the cuvette) are developed. Numerical characterization is performed comparing SPICE analysis and FDTD simulations. Experimental characterization on a built prototype is carried out by means of a wideband frequency voltage sensor. A good level of consistency is obtained between the numerical and the experimental voltage intensities measured across the cuvette electrodes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.