A unique cytotoxic metabolite, turbinamide (1), has been isolated from the marine tunicate Sidnyum turbinatum through a bioassay-guided approach. Its structure has been elucidated by an extensive spectroscopic analysis. Turbinamide demonstrated a strong and selective cytotoxic effect against neuronal cells rather than immune system cells.
Turbinamide, a new selective cytotoxic agent from the Mediterranean tunicate Sidnyum turbinatum / Aiello, A; Carbonelli, S; Esposito, Giuseppe; Fattorusso, E; Iuvone, T; Menna, M.. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 3:(2001), pp. 2941-2944. [10.1021/ol016164h]
Turbinamide, a new selective cytotoxic agent from the Mediterranean tunicate Sidnyum turbinatum.
ESPOSITO, GIUSEPPE;
2001
Abstract
A unique cytotoxic metabolite, turbinamide (1), has been isolated from the marine tunicate Sidnyum turbinatum through a bioassay-guided approach. Its structure has been elucidated by an extensive spectroscopic analysis. Turbinamide demonstrated a strong and selective cytotoxic effect against neuronal cells rather than immune system cells.File allegati a questo prodotto
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
