Innate immunity is the host defensive weapon against pathogens and this issue of Blood offers an interesting new bullet for the immune system gun by studying the role of Toll-like receptor 2 (TLR2) in megakaryocytic function; a field previously not explored. Beaulieu and colleagues provide evidence that inflammation, through TLR2, can increase megakaryocyte maturation and modulate its phenotype, contributing to our understanding of the interrelationship between inflammation and hemostasis.
Megakaryocyte TLR2: immunity bullet? / Pignatelli, Pasquale; Carnevale, Roberto. - In: BLOOD. - ISSN 0006-4971. - ELETTRONICO. - 117:22(2011), pp. 5791-5792. [10.1182/blood-2011-04-346718]
Megakaryocyte TLR2: immunity bullet?
PIGNATELLI, Pasquale;CARNEVALE, Roberto
2011
Abstract
Innate immunity is the host defensive weapon against pathogens and this issue of Blood offers an interesting new bullet for the immune system gun by studying the role of Toll-like receptor 2 (TLR2) in megakaryocytic function; a field previously not explored. Beaulieu and colleagues provide evidence that inflammation, through TLR2, can increase megakaryocyte maturation and modulate its phenotype, contributing to our understanding of the interrelationship between inflammation and hemostasis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
