Background and purpose: The pathology of neuropsychological deficits in Parkinsons disease (PD) is incompletely defined. Methods: We investigated cortical thickness and neuropsychological performances in non-demented patients with PD and healthy controls. Results: Patients showed significant cortical thinning in right middle temporal and left fusiform cortices. Verbal memory performance was related with left fusiform thinning. Conclusions: Cognitive and cortical changes in non-demented patients with PD are detectable and clearly related.
Regional cortical thickness and cognitive functions in non-demented Parkinson's disease patients: a pilot study / Pellicano, Clelia; F., Assogna; F., Piras; C., Caltagirone; G., Spalletta; Pontieri, FRANCESCO ERNESTO. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - STAMPA. - 19:1(2012), pp. 172-175. [10.1111/j.1468-1331.2011.03465.x]
Regional cortical thickness and cognitive functions in non-demented Parkinson's disease patients: a pilot study
PELLICANO, CLELIA;PONTIERI, FRANCESCO ERNESTO
2012
Abstract
Background and purpose: The pathology of neuropsychological deficits in Parkinsons disease (PD) is incompletely defined. Methods: We investigated cortical thickness and neuropsychological performances in non-demented patients with PD and healthy controls. Results: Patients showed significant cortical thinning in right middle temporal and left fusiform cortices. Verbal memory performance was related with left fusiform thinning. Conclusions: Cognitive and cortical changes in non-demented patients with PD are detectable and clearly related.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
