4-Substituted alpha-ylidene-gamma-butyrolactones produce N-ethoxycarbonyl-spiroaziridino gamma-lactone diastereomers on treatment with NsONHCO(2)Et and CaO. A good stereofacial preference is observed when the ring substituent is a phenyl group. These products are precursors of alpha-aminolactone as pure diastereomers.
Spiroaziridines from 4-substituted alpha-ylidene-gamma-butyro lactones / Gasperi, T.; Loreto, Maria Antonietta; Migliorini, Antonella; Tardella, Paolo Antonio. - In: HETEROCYCLES. - ISSN 0385-5414. - STAMPA. - 65:6(2005), pp. 1447-1454. [10.3987/COM-05-10376]
Spiroaziridines from 4-substituted alpha-ylidene-gamma-butyro lactones
LORETO, Maria Antonietta;MIGLIORINI, Antonella;TARDELLA, Paolo Antonio
2005
Abstract
4-Substituted alpha-ylidene-gamma-butyrolactones produce N-ethoxycarbonyl-spiroaziridino gamma-lactone diastereomers on treatment with NsONHCO(2)Et and CaO. A good stereofacial preference is observed when the ring substituent is a phenyl group. These products are precursors of alpha-aminolactone as pure diastereomers.File allegati a questo prodotto
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