Background and Purpose - Adventitial vasa vasorum and plaque vascularization have been established as predictors of unstable atheromasic lesions in cerebro- and cardiovascular patients. Ultrasound contrast agents provide reliable information on tissue perfusion and microcirculation. We used contrast ultrasound duplex scanning to identify carotid plaque vascularization. Methods - Contrast carotid duplex scanning was performed in 23 patients with plaques of different degree of stenosis and echogenicity. Results - Plaque vascularization was detected in the fibrous and fibro-fatty tissue and not observed in the calcific nor in the necrotic and hemorrhagic tissue. Constantly, a small vessel was observed under ulcerations. Conclusions - Carotid contrast ultrasound imaging appears to be an emerging technique for identifying plaque angiogenesis. Further studies are needed to clarify the role of plaque angiogenesis for assessing cerebrovascular risk and to monitor effects of therapies aimed to plaque remodelling.

Detection of carotid adventitial vasa vasorum and plaque vascularization with ultrasound cadence contrast pulse sequencing technique and echo-contrast agent / Edoardo, Vicenzini; Giannoni, Maria Fabrizia; Puccinelli, Francesco; Ricciardi, Maria Chiara; M., Altieri; DI PIERO, Vittorio; Gossetti, Bruno; BENEDETTI VALENTINI, Fabrizio; Lenzi, Gian Luigi. - In: STROKE. - ISSN 0039-2499. - STAMPA. - 38:10(2007), pp. 2841-2843. [10.1161/strokeaha.107.487918]

Detection of carotid adventitial vasa vasorum and plaque vascularization with ultrasound cadence contrast pulse sequencing technique and echo-contrast agent

GIANNONI, Maria Fabrizia;PUCCINELLI, FRANCESCO;RICCIARDI, Maria Chiara;DI PIERO, Vittorio;GOSSETTI, Bruno;BENEDETTI VALENTINI, Fabrizio;LENZI, Gian Luigi
2007

Abstract

Background and Purpose - Adventitial vasa vasorum and plaque vascularization have been established as predictors of unstable atheromasic lesions in cerebro- and cardiovascular patients. Ultrasound contrast agents provide reliable information on tissue perfusion and microcirculation. We used contrast ultrasound duplex scanning to identify carotid plaque vascularization. Methods - Contrast carotid duplex scanning was performed in 23 patients with plaques of different degree of stenosis and echogenicity. Results - Plaque vascularization was detected in the fibrous and fibro-fatty tissue and not observed in the calcific nor in the necrotic and hemorrhagic tissue. Constantly, a small vessel was observed under ulcerations. Conclusions - Carotid contrast ultrasound imaging appears to be an emerging technique for identifying plaque angiogenesis. Further studies are needed to clarify the role of plaque angiogenesis for assessing cerebrovascular risk and to monitor effects of therapies aimed to plaque remodelling.
2007
cadence cps technique; carotid atherosclerosis; echo-contrast agents; key words: carotid atherosclerosis plaque vascularization ultrasonography echo-contrast agents cadence cps technique; plaque vascularization; ultrasonography
01 Pubblicazione su rivista::01a Articolo in rivista
Detection of carotid adventitial vasa vasorum and plaque vascularization with ultrasound cadence contrast pulse sequencing technique and echo-contrast agent / Edoardo, Vicenzini; Giannoni, Maria Fabrizia; Puccinelli, Francesco; Ricciardi, Maria Chiara; M., Altieri; DI PIERO, Vittorio; Gossetti, Bruno; BENEDETTI VALENTINI, Fabrizio; Lenzi, Gian Luigi. - In: STROKE. - ISSN 0039-2499. - STAMPA. - 38:10(2007), pp. 2841-2843. [10.1161/strokeaha.107.487918]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/366206
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 22
  • Scopus 116
  • ???jsp.display-item.citation.isi??? 86
social impact