Understanding the mechanism by which a polypeptide chain folds into its native structure is a central problem of modern biophysics. The collaborative efforts of experimental and theoretical studies recently raised the tantalizing possibility to define a unifying mechanism for protein folding. In this review we summarize some of these intriguing advances and analyze them together with a discussion on the new findings concerning the so-called downhill folding.
Mechanisms of protein folding / Ivarsson, Y; TRAVAGLINI ALLOCATELLI, Carlo; Brunori, Maurizio; Gianni, Stefano. - In: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. - ISSN 0175-7571. - 37:(2008), pp. 721-728. [10.1007/s00249-007-0256-x]
Mechanisms of protein folding.
TRAVAGLINI ALLOCATELLI, Carlo;BRUNORI, Maurizio;GIANNI, STEFANO
2008
Abstract
Understanding the mechanism by which a polypeptide chain folds into its native structure is a central problem of modern biophysics. The collaborative efforts of experimental and theoretical studies recently raised the tantalizing possibility to define a unifying mechanism for protein folding. In this review we summarize some of these intriguing advances and analyze them together with a discussion on the new findings concerning the so-called downhill folding.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
