The utilisation of NMR fingerprinting is proposed as a rapid, available and reliable method to determine the contamination of herbal products. The presence of nimesulide has been reported recently as the contaminant of P.C. 28 Plus, a product based on herbal drugs marketed by the Italian company Cosval. The presence of the substance, as well as its relevant concentration (5%), was first reported by HPLC/MS analysis by other authors. The use of an NMR fingerprint confirmed the previous contamination with nimesulide in P.C. 28 Plus. The same contaminant was also found in P.C. 28 Pink. Furthermore, an analysis of Alergix Plus, another product of the same factory, evidenced the presence of bromhexin. © 2010 Taylor & Francis.

Contaminations of herbal products determined by NMR fingerprint / Nicoletti, Marcello; Petitto, Valentina. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6419. - STAMPA. - 24:14(2010), pp. 1325-1329. [10.1080/14786410903368670]

Contaminations of herbal products determined by NMR fingerprint

NICOLETTI, Marcello;PETITTO, Valentina
2010

Abstract

The utilisation of NMR fingerprinting is proposed as a rapid, available and reliable method to determine the contamination of herbal products. The presence of nimesulide has been reported recently as the contaminant of P.C. 28 Plus, a product based on herbal drugs marketed by the Italian company Cosval. The presence of the substance, as well as its relevant concentration (5%), was first reported by HPLC/MS analysis by other authors. The use of an NMR fingerprint confirmed the previous contamination with nimesulide in P.C. 28 Plus. The same contaminant was also found in P.C. 28 Pink. Furthermore, an analysis of Alergix Plus, another product of the same factory, evidenced the presence of bromhexin. © 2010 Taylor & Francis.
2010
pharmacovigilance; bromhexin; adhatoda vasica; herbal product; nmr fingerprint; contamination; nimesulide
01 Pubblicazione su rivista::01a Articolo in rivista
Contaminations of herbal products determined by NMR fingerprint / Nicoletti, Marcello; Petitto, Valentina. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6419. - STAMPA. - 24:14(2010), pp. 1325-1329. [10.1080/14786410903368670]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/365924
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 4
social impact