A novel member of a new class of chiral uranyl±salophen complexes has been synthesised. The chiral recognition ability of this receptor toward the enantiomers of two primary amines, a sulfoxide, and a quaternary ammonium chloride has been evaluated for the first time. The enantioselectivities obtained are encouraging. The NMR method developed for this purpose allows a fast, quantitative determination of the enantioselectivity of the host directly from its racemic mixture and could find application as a preliminary screening tool in the search for new receptors using combinatorial methods. The experiments carried out in this context demonstrated also that the activation barrier for the racemisation of such chiral uranyl±salophen receptors is much higher than the lower limit of 21 kcalmol1 previously reported.

Evaluation of chiral recognition ability of a novel uranyl-salophen-based receptor: An easy and rapid testing protocol / DALLA CORT, Antonella; Pasquini, Chiara; J., MIRANDA MURUA; M., Pons; L., Schiaffino. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - STAMPA. - 10:(2004), pp. 3301-3307. [10.1002/chem.200400016]

Evaluation of chiral recognition ability of a novel uranyl-salophen-based receptor: An easy and rapid testing protocol

DALLA CORT, Antonella;PASQUINI, CHIARA;
2004

Abstract

A novel member of a new class of chiral uranyl±salophen complexes has been synthesised. The chiral recognition ability of this receptor toward the enantiomers of two primary amines, a sulfoxide, and a quaternary ammonium chloride has been evaluated for the first time. The enantioselectivities obtained are encouraging. The NMR method developed for this purpose allows a fast, quantitative determination of the enantioselectivity of the host directly from its racemic mixture and could find application as a preliminary screening tool in the search for new receptors using combinatorial methods. The experiments carried out in this context demonstrated also that the activation barrier for the racemisation of such chiral uranyl±salophen receptors is much higher than the lower limit of 21 kcalmol1 previously reported.
2004
01 Pubblicazione su rivista::01a Articolo in rivista
Evaluation of chiral recognition ability of a novel uranyl-salophen-based receptor: An easy and rapid testing protocol / DALLA CORT, Antonella; Pasquini, Chiara; J., MIRANDA MURUA; M., Pons; L., Schiaffino. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - STAMPA. - 10:(2004), pp. 3301-3307. [10.1002/chem.200400016]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/365629
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 20
  • ???jsp.display-item.citation.isi??? 21
social impact