The evaluation of a series of piperazinyl carbamates and ureas, designed on the basis of previously reported TRPV1 antagonists and FAAH inhibitors, led to the identification of some 'dual-action' compounds targeting both FAAH and TRPV1 or TRPA1 receptors. © 2009 Elsevier Ltd. All rights reserved.

Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands / Morera, Enrico; Luciano De, Petrocellis; Morera, Ludovica; Aniello Schiano, Moriello; Alessia, Ligresti; Nalli, Marianna; David F., Woodward; Vincenzo Di, Marzo; Ortar, Giorgio. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 19:23(2009), pp. 6806-6809. [10.1016/j.bmcl.2009.09.033]

Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands

MORERA, ENRICO;MORERA, LUDOVICA;NALLI, Marianna;ORTAR, Giorgio
2009

Abstract

The evaluation of a series of piperazinyl carbamates and ureas, designed on the basis of previously reported TRPV1 antagonists and FAAH inhibitors, led to the identification of some 'dual-action' compounds targeting both FAAH and TRPV1 or TRPA1 receptors. © 2009 Elsevier Ltd. All rights reserved.
2009
dual-ligands; faah; fatty acid amide hydrolase; piperazinyl carbamates; transient receptor potential channels; trpa1; trpv1
01 Pubblicazione su rivista::01a Articolo in rivista
Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands / Morera, Enrico; Luciano De, Petrocellis; Morera, Ludovica; Aniello Schiano, Moriello; Alessia, Ligresti; Nalli, Marianna; David F., Woodward; Vincenzo Di, Marzo; Ortar, Giorgio. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 19:23(2009), pp. 6806-6809. [10.1016/j.bmcl.2009.09.033]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/364848
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