Introduction: We describe a case of genetically proven atypical teratoid/rhabdoid tumor (ATRT), showing ultrastructural evidence of ependymal differentiation. Such differentiation has not been reported so far in ATRT. Conclusion: This finding supports the concept that ATRTs as the majority of central nervous system embryonal tumors may derive from an immature and pluripotent neuroectodermal cell capable of differentiating along multiple lineages. © 2009 Springer-Verlag.
Ultrastructural evidence of ependymal differentiation in a genetically proven atypical teratoid/rhabdoid tumor / Antonelli, Manila; Giovanna, Cenacchi; Piergiorgio, Modena; Isabella, Morra; Marco, Forni; Giangaspero, Felice. - In: CHILDS NERVOUS SYSTEM. - ISSN 0256-7040. - STAMPA. - 25:12(2009), pp. 1627-1631. [10.1007/s00381-009-0926-3]
Ultrastructural evidence of ependymal differentiation in a genetically proven atypical teratoid/rhabdoid tumor
ANTONELLI, MANILA;GIANGASPERO, FELICE
2009
Abstract
Introduction: We describe a case of genetically proven atypical teratoid/rhabdoid tumor (ATRT), showing ultrastructural evidence of ependymal differentiation. Such differentiation has not been reported so far in ATRT. Conclusion: This finding supports the concept that ATRTs as the majority of central nervous system embryonal tumors may derive from an immature and pluripotent neuroectodermal cell capable of differentiating along multiple lineages. © 2009 Springer-Verlag.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.