Conclusion: Intratympanic administration of prednisolone at a dose of 62.5 mg/ml performed every day for 3 consecutive days is more efficacious than the therapeutic approaches described so far in the literature. Objectives: The aim of the study was to evaluate the overall success rate, morbidity, and prognostic factors of a new protocol of intratympanic steroid administration as a means of primary therapy for idiopathic sensorineural hearing loss. Methods: Overall, 34 patients presenting sudden unilateral sensorineural hearing loss of at least 30 dB over three frequencies that had developed within 72 h were treated once a day for 3 consecutive days with a single intratympanic injection of prednisone diluted in saline solution. Results: Following intratympanic therapy with prednisone, 16 patients (47%) reported complete recovery of sudden sensorineural hearing loss, with a pure tone average that returned within 25 dB; 11 patients (32.3%) showed improvement in hearing of more than 30 dB; 4 patients presented improvement in pure-tone average between 10 and 30 dB. Only three patients failed to improve following intratympanic injection. © 2010 Informa Healthcare.

Intratympanic prednisolone therapy for sudden sensorineural hearing loss: A new protocol / Filipo, Roberto; Covelli, Edoardo; Balsamo, Giorgio; Attanasio, Giuseppe. - In: ACTA OTO-LARYNGOLOGICA. - ISSN 0001-6489. - 130:11(2010), pp. 1209-1213. [10.3109/00016481003793766]

Intratympanic prednisolone therapy for sudden sensorineural hearing loss: A new protocol

FILIPO, Roberto;COVELLI, EDOARDO;BALSAMO, GIORGIO;ATTANASIO, GIUSEPPE
2010

Abstract

Conclusion: Intratympanic administration of prednisolone at a dose of 62.5 mg/ml performed every day for 3 consecutive days is more efficacious than the therapeutic approaches described so far in the literature. Objectives: The aim of the study was to evaluate the overall success rate, morbidity, and prognostic factors of a new protocol of intratympanic steroid administration as a means of primary therapy for idiopathic sensorineural hearing loss. Methods: Overall, 34 patients presenting sudden unilateral sensorineural hearing loss of at least 30 dB over three frequencies that had developed within 72 h were treated once a day for 3 consecutive days with a single intratympanic injection of prednisone diluted in saline solution. Results: Following intratympanic therapy with prednisone, 16 patients (47%) reported complete recovery of sudden sensorineural hearing loss, with a pure tone average that returned within 25 dB; 11 patients (32.3%) showed improvement in hearing of more than 30 dB; 4 patients presented improvement in pure-tone average between 10 and 30 dB. Only three patients failed to improve following intratympanic injection. © 2010 Informa Healthcare.
2010
acoustic nerve; audiometric test; cochlea; deafness; dizziness; prednisolone; pure tone average; tinnitus
01 Pubblicazione su rivista::01a Articolo in rivista
Intratympanic prednisolone therapy for sudden sensorineural hearing loss: A new protocol / Filipo, Roberto; Covelli, Edoardo; Balsamo, Giorgio; Attanasio, Giuseppe. - In: ACTA OTO-LARYNGOLOGICA. - ISSN 0001-6489. - 130:11(2010), pp. 1209-1213. [10.3109/00016481003793766]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/363728
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