Stroke is the first cause of disability in industrialized countries. Thus, understanding the mechanisms of poststroke recovery appears to be crucial in improving motor performance and reducing disability in stroke patients. Strategies through which brain restores lost functions after ischemic lesions are numerous. The mechanisms underlying poststroke recovery, known as cerebral plasticity, are so far hypothetical. However, fuctional magnetic resonance imaging (fMRI) studies recently, have provided new insights in to stroke recovery. This article sketches out the mechanisms that are thought to underly recovery and focuses on fMRI experimental studies that have investigated the influence of a number of drugs on functional recovery. Functional MRI is a valuable tool in understanding functional recovery and mail help to disclose new therapeutical approaches.
Functional MRI, drugs, and poststroke recovery / D., Tombari; M. C., Ricciardi; N., Bonaffini; M., Pasquini; Cecconi, Emanuela; DI PIERO, Vittorio; Lenzi, Gian Luigi. - In: CLINICAL AND EXPERIMENTAL HYPERTENSION. - ISSN 1064-1963. - 28:3-4(2006), pp. 301-307. (Intervento presentato al convegno 1st Chieti Stroke Meeting tenutosi a Chieti, ITALY nel SEP 06, 2004) [10.1080/10641960600549348].
Functional MRI, drugs, and poststroke recovery
CECCONI, EMANUELA;DI PIERO, Vittorio;LENZI, Gian Luigi
2006
Abstract
Stroke is the first cause of disability in industrialized countries. Thus, understanding the mechanisms of poststroke recovery appears to be crucial in improving motor performance and reducing disability in stroke patients. Strategies through which brain restores lost functions after ischemic lesions are numerous. The mechanisms underlying poststroke recovery, known as cerebral plasticity, are so far hypothetical. However, fuctional magnetic resonance imaging (fMRI) studies recently, have provided new insights in to stroke recovery. This article sketches out the mechanisms that are thought to underly recovery and focuses on fMRI experimental studies that have investigated the influence of a number of drugs on functional recovery. Functional MRI is a valuable tool in understanding functional recovery and mail help to disclose new therapeutical approaches.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
