The early stages of aggregation kinetics in a binary mixture of asymmetric colloids, aggregating irreversibly via biotin-streptavidin bonds, are experimentally and numerically studied. Experiments are performed by DLS methods, and data are analyzed in terms of a Smoluchowski-like coagulation equation. Focus is on the case of small (S) biotin-covered particles interacting with large (L) streptavidin-covered ones. The small particles act as linkers between the large ones. The dependence of S-L and L-L aggregation rate constants on the ratio between concentration of small and large particles is investigated, to detect the concentration at which aggregation of large particles is most effective.
Assembly Kinetics in Binary Mixtures of Strongly Attractive Colloids / Neda, Ghofraniha; Andreozzi, Patrizia; Russo, John; LA MESA, Camillo; Sciortino, Francesco. - In: JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL. - ISSN 1520-6106. - STAMPA. - 113:19(2009), pp. 6775-6781. [10.1021/jp807999n]