The aim of this study is to evaluate whether traffic police exposed to urban pollutants could be at risk of changes on proliferative response of blood lympho-monocytes to the mitogen phytohemagglutinin (PHA) compared to a control group. Traffic police were matched with controls by sex, age, length of service, drinking habits and smoking habits after excluding main confounding factors. So, 77 traffic police exposed to urban pollutants (43 men and 34 women) and 77 controls with indoor activity (43 men and 34 women) were included in the study. The proliferative response of blood lympho-monocytes to the mitogen PHA was significantly lower in male and female traffic police compared to controls (respectively, P = 0.000 and 0.014). The possibility of an effect on immune system and therefore on the blood lympho-monocytes proliferative answer in traffic police exposed to urban pollutants, can be assumed. (C) 2004 Published by Elsevier B.V.
Response of lympho-monocytes to phytohemagglutinin in urban workers / Tomei, Francesco; Rosati, Maria Valeria; Tiziana Paola, Baccolo; Andrea, Bernardini; Ciarrocca, Manuela; Tiziana, Caciari; Enrico, Tomao. - In: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY. - ISSN 1382-6689. - 17:1(2004), pp. 13-18. [10.1016/j.etap.2004.01.004]
Response of lympho-monocytes to phytohemagglutinin in urban workers
TOMEI, Francesco;ROSATI, Maria Valeria;CIARROCCA, Manuela;
2004
Abstract
The aim of this study is to evaluate whether traffic police exposed to urban pollutants could be at risk of changes on proliferative response of blood lympho-monocytes to the mitogen phytohemagglutinin (PHA) compared to a control group. Traffic police were matched with controls by sex, age, length of service, drinking habits and smoking habits after excluding main confounding factors. So, 77 traffic police exposed to urban pollutants (43 men and 34 women) and 77 controls with indoor activity (43 men and 34 women) were included in the study. The proliferative response of blood lympho-monocytes to the mitogen PHA was significantly lower in male and female traffic police compared to controls (respectively, P = 0.000 and 0.014). The possibility of an effect on immune system and therefore on the blood lympho-monocytes proliferative answer in traffic police exposed to urban pollutants, can be assumed. (C) 2004 Published by Elsevier B.V.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
