Methods for protein structure prediction are flourishing and becoming widely available to both experimentalists and computational biologists. However, how good are they? What is their range of applicability and how can we know which method is better suited for the task at hand? These are the questions that this review tries to address, by describing the worldwide Critical Assessment of techniques for protein Structure Prediction (CASP) initiative and focusing on the specific problems of assessing the quality of a protein 3D model.

The Evaluation of Protein Structure Prediction Results / Cozzetto, Domenico; Giorgetti, A; Raimondo, Domenico; Tramontano, Anna. - In: MOLECULAR BIOTECHNOLOGY. - ISSN 1073-6085. - STAMPA. - 39:(2008), pp. 43-57. [10.1007/s12033-007-9023-6]

The Evaluation of Protein Structure Prediction Results

COZZETTO, Domenico;RAIMONDO, Domenico;TRAMONTANO, ANNA
2008

Abstract

Methods for protein structure prediction are flourishing and becoming widely available to both experimentalists and computational biologists. However, how good are they? What is their range of applicability and how can we know which method is better suited for the task at hand? These are the questions that this review tries to address, by describing the worldwide Critical Assessment of techniques for protein Structure Prediction (CASP) initiative and focusing on the specific problems of assessing the quality of a protein 3D model.
2008
protein structure prediction; accuracy of protein structure models; CASP; structure prediction servers; metapredictors
01 Pubblicazione su rivista::01a Articolo in rivista
The Evaluation of Protein Structure Prediction Results / Cozzetto, Domenico; Giorgetti, A; Raimondo, Domenico; Tramontano, Anna. - In: MOLECULAR BIOTECHNOLOGY. - ISSN 1073-6085. - STAMPA. - 39:(2008), pp. 43-57. [10.1007/s12033-007-9023-6]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/360380
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