This is a case report on two young infertile brothers carrying a reciprocal translocation showing severe sperm ultrastructural defects. Germ cells immaturity, diffuse cell apoptosis and necrosis were evident. Sperm heads were abnormal and pleomorphic, with poorly developed acrosomes. Double/multiple fused or decapitated sperm and "lasso-like" tails were observed. Axonemes were mostly rolled up.
Seminal ultrastructure of two infertile brothers carrying a maternally-inherited reciprocal translocation t(10;15)(p12;q21) / HEYN SALINAS, Rosemari Brigitte; Familiari, Giuseppe; Latini, M; Relucenti, Michela; Petruzziello, Luciano; Gandini, L; Lenzi, A.. - In: INTERNATIONAL JOURNAL OF ANDROLOGY. - ISSN 0105-6263. - STAMPA. - 31 (Suppl. 1):(2008), pp. 6-6. (Intervento presentato al convegno 5th European Congress of Andrology tenutosi a Roma (Italia) nel 26-28 novembre 2008) [10.1111/j.1365-2605.2008.00917.x].
Seminal ultrastructure of two infertile brothers carrying a maternally-inherited reciprocal translocation t(10;15)(p12;q21)
HEYN SALINAS, Rosemari Brigitte;FAMILIARI, Giuseppe;RELUCENTI, Michela;PETRUZZIELLO, LUCIANO;LENZI A.
2008
Abstract
This is a case report on two young infertile brothers carrying a reciprocal translocation showing severe sperm ultrastructural defects. Germ cells immaturity, diffuse cell apoptosis and necrosis were evident. Sperm heads were abnormal and pleomorphic, with poorly developed acrosomes. Double/multiple fused or decapitated sperm and "lasso-like" tails were observed. Axonemes were mostly rolled up.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
