A new approach for the preparation of hydrophilic and biocompatible porous scaffolds is described. The procedure involves the derivatization of a biopolymer by the introduction of vinylic moieties, formation of a high-internal-phase oil-in-water emulsion, and its subsequent polymerization. The ensuing materials are characterized by a highly porous morphology represented by pores completely interconnected by a plurality of holes. The hydrophilic and biocompatible nature of these materials make them good candidates for application as scaffolds for tissue engineering.
Scaffolds based on biopolymeric foams / Barbetta, Andrea; Dentini, Mariella; M. S., De Vecchis; P., Filippini; G., Formisano; S., Caiazza. - In: ADVANCED FUNCTIONAL MATERIALS. - ISSN 1616-301X. - STAMPA. - 15:1(2005), pp. 118-124. [10.1002/adfm.200400072]
Scaffolds based on biopolymeric foams
BARBETTA, ANDREA;DENTINI, Mariella;
2005
Abstract
A new approach for the preparation of hydrophilic and biocompatible porous scaffolds is described. The procedure involves the derivatization of a biopolymer by the introduction of vinylic moieties, formation of a high-internal-phase oil-in-water emulsion, and its subsequent polymerization. The ensuing materials are characterized by a highly porous morphology represented by pores completely interconnected by a plurality of holes. The hydrophilic and biocompatible nature of these materials make them good candidates for application as scaffolds for tissue engineering.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
