One color, mass selected resonant two-photon ionization (IcR2PI) spectra of supersonically expanded bare neurotransmitter, (I S,2S)-(+)-N-methyl pseudoephedrine (MPE), and its complexes with chiral and achiral molecules have been investigated. The excitation spectrum of bare MPE has been analyzed and discussed on the basis of theoretical predictions at the B3LYP/6-31G** level of theory. The results allowed to get information on the possible conformers of MPE molecule and on the intermolecular forces on its cluster formed with a variety of solvent molecules, including chiral alcohols, lactates and water. Further information on intermolecular interactions have been obtained with ESI-CID-MS2 technique, applied to chiral biomolecules linked through a metal ion to the neurotransmitter. The experimental results are compared with theoretical predictions. (c) 2007 Elsevier B.V. All rights reserved.
Laser R2PI spectroscopic and mass spectrometric studies of chiral neurotransmitters / Giardini, Anna; V., Marotta; Paladini, Alessandra; S., Piccirillo; Rondino, Flaminia; Satta, Mauro; Speranza, Maurizio. - In: APPLIED SURFACE SCIENCE. - ISSN 0169-4332. - STAMPA. - 253:19(2007), pp. 7767-7772. (Intervento presentato al convegno Symposium on Photon-Assisted Synthesis and Processing of Functional Materials held at the 2006 EMRS Spring Meeting tenutosi a Nice, FRANCE nel MAY 29-JUN 02, 2006) [10.1016/j.apsusc.2007.02.082].
Laser R2PI spectroscopic and mass spectrometric studies of chiral neurotransmitters
GIARDINI, Anna;PALADINI, Alessandra;RONDINO, Flaminia;SATTA, Mauro;SPERANZA, Maurizio
2007
Abstract
One color, mass selected resonant two-photon ionization (IcR2PI) spectra of supersonically expanded bare neurotransmitter, (I S,2S)-(+)-N-methyl pseudoephedrine (MPE), and its complexes with chiral and achiral molecules have been investigated. The excitation spectrum of bare MPE has been analyzed and discussed on the basis of theoretical predictions at the B3LYP/6-31G** level of theory. The results allowed to get information on the possible conformers of MPE molecule and on the intermolecular forces on its cluster formed with a variety of solvent molecules, including chiral alcohols, lactates and water. Further information on intermolecular interactions have been obtained with ESI-CID-MS2 technique, applied to chiral biomolecules linked through a metal ion to the neurotransmitter. The experimental results are compared with theoretical predictions. (c) 2007 Elsevier B.V. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
