Deep Brain Stimulation (DBS) has revealed a convincing clinical efficacy in Parkinson's diseases and essential tremor. Unfortunately, to date no clear understanding of the therapeutic mechanisms has been achieved. Characterization of the distribution of the electrical quantities inside the target areas of the central nervous system is one fundamental step ahead. Starting from the studies that so far addressed this issue, aim of this work is to quantify the role of some parameters, such as dimensions of the conducting domain and of boundary conditions, on the distribution of the fundamental electric quantities inside the brain target area.
Fundamental Electrical Quantities in Deep Brain Stimulation: Influence of Domain Dimensions and Boundary Conditions / Liberti, Micaela; Apollonio, Francesca; Paffi, Alessandra; M., Parazzini; F., Maggio; T., Novellino; P., Ravazzani; D'Inzeo, Guglielmo. - STAMPA. - (2007), pp. 6668-6671. (Intervento presentato al convegno 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society tenutosi a Lion, France nel 22-26 August 2007) [10.1109/IEMBS.2007.4353889].
Fundamental Electrical Quantities in Deep Brain Stimulation: Influence of Domain Dimensions and Boundary Conditions
LIBERTI, Micaela;APOLLONIO, Francesca;PAFFI, ALESSANDRA;D'INZEO, Guglielmo
2007
Abstract
Deep Brain Stimulation (DBS) has revealed a convincing clinical efficacy in Parkinson's diseases and essential tremor. Unfortunately, to date no clear understanding of the therapeutic mechanisms has been achieved. Characterization of the distribution of the electrical quantities inside the target areas of the central nervous system is one fundamental step ahead. Starting from the studies that so far addressed this issue, aim of this work is to quantify the role of some parameters, such as dimensions of the conducting domain and of boundary conditions, on the distribution of the fundamental electric quantities inside the brain target area.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
