A liquid chromatography/electrospray (ESI)–tandem mass spectrometric method for the measurement of aflatoxin M1 (AFM1) in milk is described. Milk sample after protein precipitation with acetone was cleaned-up with a Carbograph-4 cartridge. Performances of the ESI source were compared with those of the atmospheric pressure photoionization source (APPI). Although a method quantification limit (MQL) of 6 ng/kg could be achieved operating with APPI source with respect to an MQL of 12 ng/kg with ESI, all the other performances being similar, then ESI was preferred as being more robust and widespread at present.

Liquid Chromatography/Tandem Mass Spectrometric Confirmatory Method for Determining Aflatoxin M1 in Cow Milk. Comparison Between Electrospray and Atmospheric Pressure Photoionization Sources / Cavaliere, Chiara; Foglia, Patrizia; E., Pastorini; Samperi, Roberto; Lagana', Aldo. - In: JOURNAL OF CHROMATOGRAPHY A. - ISSN 0021-9673. - STAMPA. - 1101:1-2(2006), pp. 69-78. [10.1016/j.chroma.2005.09.060]

Liquid Chromatography/Tandem Mass Spectrometric Confirmatory Method for Determining Aflatoxin M1 in Cow Milk. Comparison Between Electrospray and Atmospheric Pressure Photoionization Sources

CAVALIERE, CHIARA;FOGLIA, Patrizia;SAMPERI, Roberto;LAGANA', Aldo
2006

Abstract

A liquid chromatography/electrospray (ESI)–tandem mass spectrometric method for the measurement of aflatoxin M1 (AFM1) in milk is described. Milk sample after protein precipitation with acetone was cleaned-up with a Carbograph-4 cartridge. Performances of the ESI source were compared with those of the atmospheric pressure photoionization source (APPI). Although a method quantification limit (MQL) of 6 ng/kg could be achieved operating with APPI source with respect to an MQL of 12 ng/kg with ESI, all the other performances being similar, then ESI was preferred as being more robust and widespread at present.
2006
Aflatoxin M1; Mycotoxins; Milk; Solid-phase extraction; Liquid chromatography; ESI-MS/MS
01 Pubblicazione su rivista::01a Articolo in rivista
Liquid Chromatography/Tandem Mass Spectrometric Confirmatory Method for Determining Aflatoxin M1 in Cow Milk. Comparison Between Electrospray and Atmospheric Pressure Photoionization Sources / Cavaliere, Chiara; Foglia, Patrizia; E., Pastorini; Samperi, Roberto; Lagana', Aldo. - In: JOURNAL OF CHROMATOGRAPHY A. - ISSN 0021-9673. - STAMPA. - 1101:1-2(2006), pp. 69-78. [10.1016/j.chroma.2005.09.060]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/358390
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