Abstract Transient mutism was observed in a liver transplant patient under immunosuppressant therapy with cyclosporine A and antifungal prophylaxis with amphotericin B. Fluid-attenuated inversion recovery and diffusion-weighted images revealed reversible bilateral symmetric hyperintensity located in the frontal motor cortex and corticospinal tracts. These MRI abnormalities may be caused by acute edema, possibly a combination of cytotoxic and vasogenic edema, which resolved with a prompt change in therapy.
Reversible diffusion MRI abnormalities and transient mutism after liver transplantation / Bianco, Federico; Fattapposta, Francesco; Locuratolo, Nicoletta; Pierallini, Alberto; Rossi, Massimo; Ruberto, F; Bozzao, Luigi. - In: NEUROLOGY. - ISSN 0028-3878. - 62:6(2004), pp. 981-983. [10.1212/01.WNL.0000115394.90984.FD]
Reversible diffusion MRI abnormalities and transient mutism after liver transplantation.
BIANCO, Federico;FATTAPPOSTA, FRANCESCO;LOCURATOLO, NICOLETTA;PIERALLINI, Alberto;ROSSI, MASSIMO;RUBERTO F;BOZZAO, Luigi
2004
Abstract
Abstract Transient mutism was observed in a liver transplant patient under immunosuppressant therapy with cyclosporine A and antifungal prophylaxis with amphotericin B. Fluid-attenuated inversion recovery and diffusion-weighted images revealed reversible bilateral symmetric hyperintensity located in the frontal motor cortex and corticospinal tracts. These MRI abnormalities may be caused by acute edema, possibly a combination of cytotoxic and vasogenic edema, which resolved with a prompt change in therapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
