In this study, we investigated the immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in guinea pig and rat isolated pancreatic acini. In dispersed acinar cells from guinea pig, immunofluorescence staining detected similar densities of NK-1 and NK-3 receptors; conversely, rat acinar cells expressed NK-1 receptors more strongly than NK-3 receptors. In line with previous functional studies, these immumocytochemical findings suggest that guinea pig NK-1 and NK-3 receptors and rat NK-1 receptors alone play a direct stimulatory role in the basal pancreatic acinar amylase release. (c) 2005 Elsevier Inc. All rights reserved.

Immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in isolated pancreatic acini of guinea pigs and rats / Broccardo, Maria; M., Teresa Ciotti; Linari, Giorgio; Agostini, Simona; Petrella, Carla; Giusy, Amadoro; Cinzia, Severini; Improta, Giovanna. - In: PEPTIDES. - ISSN 0196-9781. - 26:11(2005), pp. 2351-2354. [10.1016/j.peptides.2005.04.022]

Immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in isolated pancreatic acini of guinea pigs and rats

BROCCARDO, Maria;LINARI, Giorgio;AGOSTINI, SIMONA;PETRELLA, CARLA;IMPROTA, Giovanna
2005

Abstract

In this study, we investigated the immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in guinea pig and rat isolated pancreatic acini. In dispersed acinar cells from guinea pig, immunofluorescence staining detected similar densities of NK-1 and NK-3 receptors; conversely, rat acinar cells expressed NK-1 receptors more strongly than NK-3 receptors. In line with previous functional studies, these immumocytochemical findings suggest that guinea pig NK-1 and NK-3 receptors and rat NK-1 receptors alone play a direct stimulatory role in the basal pancreatic acinar amylase release. (c) 2005 Elsevier Inc. All rights reserved.
2005
guinea pig; immunofluorescence; pancreatic acini; rat; tachykinin receptors
01 Pubblicazione su rivista::01a Articolo in rivista
Immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in isolated pancreatic acini of guinea pigs and rats / Broccardo, Maria; M., Teresa Ciotti; Linari, Giorgio; Agostini, Simona; Petrella, Carla; Giusy, Amadoro; Cinzia, Severini; Improta, Giovanna. - In: PEPTIDES. - ISSN 0196-9781. - 26:11(2005), pp. 2351-2354. [10.1016/j.peptides.2005.04.022]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/357767
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