Esophageal squamous cell carcinoma is a relative common malignancy with a very poor prognosis, even adopting an integrated and multidisciplinary approach. According to the literature, gastrointestinal stromal tumors (GISTs) rarely originate from the esophagus. Moreover there are not reports of synchronous occurrence of squamous cell carcinoma and GIST at esophageal site.CASE PRESENTATION:We describe a case of a 74 year old patient who underwent surgery for squamous cell carcinoma of the lower third of the esophagus with an incidental pathologic diagnosis of a concomitant GIST in the thoracic tract. CONCLUSION: In literature there is no evidence of concomitant squamous carcinoma and GIST of the thoracic esophagus, even if esophageal GISTs are sometimes described. The occasional finding of this neoplastic lesion underlines the importance of a carefully pathological diagnosis for its identification. Surgery, followed by a multidisciplinary approach remains the first-line treatment in both squamous and stromal neoplasm.

The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site / Spinelli, GIAN PAOLO; Miele, Evelina; Tomao, Federica; Rossi, Luigi; Giulia, Pasciuti; Angelo, Zullo; Federica, Zoratto; Jose, Nunnari; CODACCI PISANELLI, Giovanni; Tomao, Silverio. - In: WORLD JOURNAL OF SURGICAL ONCOLOGY. - ISSN 1477-7819. - ELETTRONICO. - 6:1(2008), p. 116. [10.1186/1477-7819-6-116]

The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site

SPINELLI, GIAN PAOLO;MIELE, EVELINA;TOMAO, FEDERICA;ROSSI, Luigi;CODACCI PISANELLI, Giovanni;TOMAO, SILVERIO
2008

Abstract

Esophageal squamous cell carcinoma is a relative common malignancy with a very poor prognosis, even adopting an integrated and multidisciplinary approach. According to the literature, gastrointestinal stromal tumors (GISTs) rarely originate from the esophagus. Moreover there are not reports of synchronous occurrence of squamous cell carcinoma and GIST at esophageal site.CASE PRESENTATION:We describe a case of a 74 year old patient who underwent surgery for squamous cell carcinoma of the lower third of the esophagus with an incidental pathologic diagnosis of a concomitant GIST in the thoracic tract. CONCLUSION: In literature there is no evidence of concomitant squamous carcinoma and GIST of the thoracic esophagus, even if esophageal GISTs are sometimes described. The occasional finding of this neoplastic lesion underlines the importance of a carefully pathological diagnosis for its identification. Surgery, followed by a multidisciplinary approach remains the first-line treatment in both squamous and stromal neoplasm.
2008
esophagus; gist; squamous cell carcinom
01 Pubblicazione su rivista::01a Articolo in rivista
The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site / Spinelli, GIAN PAOLO; Miele, Evelina; Tomao, Federica; Rossi, Luigi; Giulia, Pasciuti; Angelo, Zullo; Federica, Zoratto; Jose, Nunnari; CODACCI PISANELLI, Giovanni; Tomao, Silverio. - In: WORLD JOURNAL OF SURGICAL ONCOLOGY. - ISSN 1477-7819. - ELETTRONICO. - 6:1(2008), p. 116. [10.1186/1477-7819-6-116]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/357673
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