The thermal condensation of formamide in the presence of mineral borates is reported. The products afforded are precursors of nucleic acids, amino acids derivatives and carboxylic acids. The efficiency and the selectivity of the reaction was studied in relation to the elemental composition of the 18 minerals analyzed. The possibility of synthesizing at the same time building blocks of both genetic and metabolic apparatuses, along with the production of amino acids, highlights the interest of the formamide/borate system in prebiotic chemistry.

The Effects of Borate Minerals on the Synthesis of Nucleic Acid Bases, Amino Acids and Biogenic Carboxylic Acids from Formamide / Raffaele, Saladino; Maurizio, Barontini; Cristina, Cossetti; DI MAURO, Ernesto; Claudia, Crestini. - In: ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE. - ISSN 0169-6149. - ELETTRONICO. - 41:4(2011), pp. 317-330. [10.1007/s11084-011-9236-3]

The Effects of Borate Minerals on the Synthesis of Nucleic Acid Bases, Amino Acids and Biogenic Carboxylic Acids from Formamide

DI MAURO, Ernesto;
2011

Abstract

The thermal condensation of formamide in the presence of mineral borates is reported. The products afforded are precursors of nucleic acids, amino acids derivatives and carboxylic acids. The efficiency and the selectivity of the reaction was studied in relation to the elemental composition of the 18 minerals analyzed. The possibility of synthesizing at the same time building blocks of both genetic and metabolic apparatuses, along with the production of amino acids, highlights the interest of the formamide/borate system in prebiotic chemistry.
2011
formamide; prebiotic chemistry; biogenic carboxylic acids; borates; nucleic acid bases
01 Pubblicazione su rivista::01a Articolo in rivista
The Effects of Borate Minerals on the Synthesis of Nucleic Acid Bases, Amino Acids and Biogenic Carboxylic Acids from Formamide / Raffaele, Saladino; Maurizio, Barontini; Cristina, Cossetti; DI MAURO, Ernesto; Claudia, Crestini. - In: ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE. - ISSN 0169-6149. - ELETTRONICO. - 41:4(2011), pp. 317-330. [10.1007/s11084-011-9236-3]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/356991
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