Rate-responsive pacemakers (PMs) aim at having pacing rates as similar to physiological cardiac rhythms as possible. The pacemaker INOS2+-CLS (Biotronik, Germany) implements a closed loop strategy (CLS) based on indirect measures of right ventricle contractility using intracardiac impedance signal. The contractility is, in turn, related to the autonomic nervous system control to the heart. Aim of this study was to evaluate the 24h beat-to-beat heart rate and blood pressure profiles in patients implanted with CLS rate adaptive PM. 24h ECG and arterial pressure waveform acquisition were performed by a digital HOLTER system by the Portapres equipment, respectively. A proper-designed algorithm was developed to classify PM pacing modalities. For each beat we estimated the heart rate (HR), and the systolic and diastolic pressure values (SP, DP). So far, 6 patients have been studied: 4 patients have been analyzed both with and without rate responsive modalities (DDD-R and DDD, respectively); 2 patients have been studied only with rate-responsive modality. Results obtained in 6 patients show that this rate adaptive PM accurately preserve the heart rate and blood pressure variability throughout the 24h. In particular, the rate adaptation of PM based on impedance measurements succeeds in maintaining the spontaneous HR, SP and DP on a beat-to-beat basis.
Scheda prodotto non validato
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo
|Titolo:||Heart rate and blood pressure variability in patients implanted with rate-responsive pacemaker.|
|Data di pubblicazione:||2004|
|Citazione:||Heart rate and blood pressure variability in patients implanted with rate-responsive pacemaker. / Censi, F; Calcagnini, G; D'Alessandro, M; Malavasi, M; Quaglione, Raffaele; Critelli, G; Bartolini, P; Barbaro, V.. - In: A QUARTERLY BULLETIN OF THE COMPUTER SOCIETY OF THE IEEE TECHNICAL COMMITTEE ON DATA ENGINEERING. - ISSN 1053-1238. - STAMPA. - 6(2004), pp. 3949-3952.|
|Appartiene alla tipologia:||01a Articolo in rivista|