Polypyrrole-polysaccharide thin films were electropolymerized from starting solutions containing pyrrole and a polysaccharide, namely, heparin, chondroitin-4-sulphate or hyaluronic acid. The synthesized samples showed good chemical and physicochemical properties determined by the synthesis parameters Such as the Current density and time. For instance, the sample morphology was strictly correlated to the current density as follows: a smooth Surface morphology was observed when the current density was in the range of 100-700 mu A/cm(2), whereas high current (1 > 1.0 mA/cm(2)) or longer time (synthesis charge > 100 mC/cm(2)) led to rough surfaces. The presence of polysaccharide within the polymeric matrix assured proper hydrophilicity to the samples. The optimized surface chemistry due to the presence of a polysaccharide and the controllable morphology allowed positive cell/substrate interactions and these are proved by cellular tests using MC3T3-E1 osteoblast Cultures. (C) 2008 Wiley Periodicals, Inc. J Biomed Mater Res 88A: 832-840, 2009

Polypyrrole-polysaccharide thin films characteristics: Electrosynthesis and biological properties / SERRA MORENO, Judit; Panero, Stefania; Materazzi, Stefano; Martinelli, Andrea; Agas, Dimitrios; Maria Giovanna, Sabbieti; Giovanni, Materazzi. - In: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. PART A. - ISSN 1549-3296. - STAMPA. - 88A:3(2009), pp. 832-840. [10.1002/jbm.a.32230]

Polypyrrole-polysaccharide thin films characteristics: Electrosynthesis and biological properties

SERRA MORENO, JUDIT;PANERO, Stefania;MATERAZZI, Stefano;MARTINELLI, Andrea;AGAS, DIMITRIOS;
2009

Abstract

Polypyrrole-polysaccharide thin films were electropolymerized from starting solutions containing pyrrole and a polysaccharide, namely, heparin, chondroitin-4-sulphate or hyaluronic acid. The synthesized samples showed good chemical and physicochemical properties determined by the synthesis parameters Such as the Current density and time. For instance, the sample morphology was strictly correlated to the current density as follows: a smooth Surface morphology was observed when the current density was in the range of 100-700 mu A/cm(2), whereas high current (1 > 1.0 mA/cm(2)) or longer time (synthesis charge > 100 mC/cm(2)) led to rough surfaces. The presence of polysaccharide within the polymeric matrix assured proper hydrophilicity to the samples. The optimized surface chemistry due to the presence of a polysaccharide and the controllable morphology allowed positive cell/substrate interactions and these are proved by cellular tests using MC3T3-E1 osteoblast Cultures. (C) 2008 Wiley Periodicals, Inc. J Biomed Mater Res 88A: 832-840, 2009
2009
cellular test; electrosynthesis; mc3t3-e1 osteoblast; polypyrrole; polysaccharide
01 Pubblicazione su rivista::01a Articolo in rivista
Polypyrrole-polysaccharide thin films characteristics: Electrosynthesis and biological properties / SERRA MORENO, Judit; Panero, Stefania; Materazzi, Stefano; Martinelli, Andrea; Agas, Dimitrios; Maria Giovanna, Sabbieti; Giovanni, Materazzi. - In: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. PART A. - ISSN 1549-3296. - STAMPA. - 88A:3(2009), pp. 832-840. [10.1002/jbm.a.32230]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/342895
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