A bonded chiral phase for HPLC, obtained by reaction between a porous silica gel modified with N(aminoethylamino)propyl groups, and A(+)[Co(en)2(NO2)] Br, was prepared in order to sepa rate optical isomers by a outer-sphere complex mechanism. The extent of the stereoselectivity of this support was tested by sampling racemates of organics acids and of tris-oxalate complexes of cobalt(III) and chromium(III). Good resolution was achieved when strong interactions of the solute (tri-oxalates complexes) with the support were involved.
"Outer-sphere ligand exchange chromatography on bonded chiral silica gel" / Carunchio, Vincenzo Tito; Messina, Antonella; M., Sinibaldi; D., Corradini. - In: JOURNAL OF LIQUID CHROMATOGRAPHY. - ISSN 0148-3919. - STAMPA. - 5:5(1982), pp. 819-828. [10.1080/01483918208060615]
"Outer-sphere ligand exchange chromatography on bonded chiral silica gel"
CARUNCHIO, Vincenzo Tito;MESSINA, Antonella;
1982
Abstract
A bonded chiral phase for HPLC, obtained by reaction between a porous silica gel modified with N(aminoethylamino)propyl groups, and A(+)[Co(en)2(NO2)] Br, was prepared in order to sepa rate optical isomers by a outer-sphere complex mechanism. The extent of the stereoselectivity of this support was tested by sampling racemates of organics acids and of tris-oxalate complexes of cobalt(III) and chromium(III). Good resolution was achieved when strong interactions of the solute (tri-oxalates complexes) with the support were involved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
