Relaxed requirements: We demonstrate the formation of adenine, hypoxanthine, and guanine from heated (130 °C), UV-irradiated formamide solutions in the absence of an inorganic catalyst. Evidence is also provided that "classical" HCN pathways for purine nucleobase production are also active in heated and UV-irradiated formamide reactions. (Chemical Equation Presented) © 2010 Wiley-VCH Verlag GmbH& Co. KGaA.

Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation / H. l., Barks; R., Buckley; Gregory A., Grieves; DI MAURO, Ernesto; Nicholas V., Hud; Thomas M., Orlando. - In: CHEMBIOCHEM. - ISSN 1439-4227. - STAMPA. - 11:9(2010), pp. 1240-1243. [10.1002/cbic.201000074]

Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation

DI MAURO, Ernesto;
2010

Abstract

Relaxed requirements: We demonstrate the formation of adenine, hypoxanthine, and guanine from heated (130 °C), UV-irradiated formamide solutions in the absence of an inorganic catalyst. Evidence is also provided that "classical" HCN pathways for purine nucleobase production are also active in heated and UV-irradiated formamide reactions. (Chemical Equation Presented) © 2010 Wiley-VCH Verlag GmbH& Co. KGaA.
2010
prebiotic syntheses; formamide; photochemistry; nitrogen heterocycles; purines
01 Pubblicazione su rivista::01a Articolo in rivista
Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation / H. l., Barks; R., Buckley; Gregory A., Grieves; DI MAURO, Ernesto; Nicholas V., Hud; Thomas M., Orlando. - In: CHEMBIOCHEM. - ISSN 1439-4227. - STAMPA. - 11:9(2010), pp. 1240-1243. [10.1002/cbic.201000074]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/31843
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