As a part of our endeavour to screen Mediterranean medicinal plants for various pharmacological activities, we evaluated antihistaminic, adaptogenic, anti-inflammatory, antinociceptive, hypotensive and locomotor properties, and antioxidant potential of Ephedra nebrodensis. 1H-NMR spectroscopy was carried out to identify the plant metabolites, which confirmed the presence of ephedrinic skeleton alkaloids. The ethanol : acetone (1 : 1) extract exhibited dose-related antihistaminic, anti-inflammatory, antinociceptive, hypotensive, antioxidant and locomotor stimulant activity. The plant bears potential for further studies.
Pharmacological activities on Ephedra nebrodensis Tineo / Mauro, Ballero; Caterina, Foddis; Cinzia, Sanna; Paolo, Scartezzini; Ferruccio, Poli; Petitto, Valentina; Serafini, Mauro; Alessandra, Stanzione; Bianco, Armandodoriano; Serrilli, ANNA MARIA; Anna Maria, Serilli; Liliana, Spina; Rosanna, Longoni; Sanjay, Kasture. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6419. - STAMPA. - 24:12(2010), pp. 1115-1124. [10.1080/14786410802680902]
Pharmacological activities on Ephedra nebrodensis Tineo
PETITTO, Valentina;SERAFINI, Mauro;BIANCO, Armandodoriano;SERRILLI, ANNA MARIA;
2010
Abstract
As a part of our endeavour to screen Mediterranean medicinal plants for various pharmacological activities, we evaluated antihistaminic, adaptogenic, anti-inflammatory, antinociceptive, hypotensive and locomotor properties, and antioxidant potential of Ephedra nebrodensis. 1H-NMR spectroscopy was carried out to identify the plant metabolites, which confirmed the presence of ephedrinic skeleton alkaloids. The ethanol : acetone (1 : 1) extract exhibited dose-related antihistaminic, anti-inflammatory, antinociceptive, hypotensive, antioxidant and locomotor stimulant activity. The plant bears potential for further studies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
