As a part of our endeavour to screen Mediterranean medicinal plants for various pharmacological activities, we evaluated antihistaminic, adaptogenic, anti-inflammatory, antinociceptive, hypotensive and locomotor properties, and antioxidant potential of Ephedra nebrodensis. 1H-NMR spectroscopy was carried out to identify the plant metabolites, which confirmed the presence of ephedrinic skeleton alkaloids. The ethanol : acetone (1 : 1) extract exhibited dose-related antihistaminic, anti-inflammatory, antinociceptive, hypotensive, antioxidant and locomotor stimulant activity. The plant bears potential for further studies.
Pharmacological activities on Ephedra nebrodensis Tineo / Mauro, B., Caterina, F., Cinzia, S., Paolo, S., Ferruccio, P., Petitto, V., Serafini, M., Alessandra, S., Bianco, A., Serrilli, A.M., Anna Maria, S., Liliana, S., Rosanna, L., Sanjay, K.. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6419. - STAMPA. - 24:12(2010), pp. 1115-1124. [10.1080/14786410802680902]
Pharmacological activities on Ephedra nebrodensis Tineo
PETITTO, Valentina;SERAFINI, Mauro;BIANCO, Armandodoriano;SERRILLI, ANNA MARIA;
2010
Abstract
As a part of our endeavour to screen Mediterranean medicinal plants for various pharmacological activities, we evaluated antihistaminic, adaptogenic, anti-inflammatory, antinociceptive, hypotensive and locomotor properties, and antioxidant potential of Ephedra nebrodensis. 1H-NMR spectroscopy was carried out to identify the plant metabolites, which confirmed the presence of ephedrinic skeleton alkaloids. The ethanol : acetone (1 : 1) extract exhibited dose-related antihistaminic, anti-inflammatory, antinociceptive, hypotensive, antioxidant and locomotor stimulant activity. The plant bears potential for further studies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
