In the present review article we sought to analyze, on the basis of a systematic review, the indications, rationale of oocytes cryopreservation, as well as the techniques that improved the aforementioned procedure in order to higher the pregnancy rate in women undergoing that procedure. Moreover, we pointed out the importance of oocytes cryopreservation in the research field as oocyte banking may be of utmost importance to increase the availability of oocytes for research applications such as genetic engineering or embryo cloning. Oocyte freezing has 25 year of history alterning successes and setbacks. Human oocytes have a delicate architecture but are freezable. Clinical efficiency remains low, but healthy children have been born, indicating that chromosomally normal embryos can originate from frozen oocytes. Freezing protocols are not yet optimal and it is now desirable to combine empirical and theoretical knowledge. (c) 2006 Elsevier Inc. All rights reserved.
Oocytes cryopreservation: State of art / G., Ambrosini; A., Andrisani; E., Porcu; E., Rebellato; A., Revelli; Caserta, Donatella; E., Cosmi; R., Marci; Moscarini, Massimo. - In: REPRODUCTIVE TOXICOLOGY. - ISSN 0890-6238. - STAMPA. - 22:2(2006), pp. 250-262. (Intervento presentato al convegno 34th Annual Conference of the European-Teratology-Society tenutosi a Abano Terme, ITALY nel SEP 03-06, 2006) [10.1016/j.reprotox.2006.04.024].
Oocytes cryopreservation: State of art
CASERTA, Donatella;MOSCARINI, Massimo
2006
Abstract
In the present review article we sought to analyze, on the basis of a systematic review, the indications, rationale of oocytes cryopreservation, as well as the techniques that improved the aforementioned procedure in order to higher the pregnancy rate in women undergoing that procedure. Moreover, we pointed out the importance of oocytes cryopreservation in the research field as oocyte banking may be of utmost importance to increase the availability of oocytes for research applications such as genetic engineering or embryo cloning. Oocyte freezing has 25 year of history alterning successes and setbacks. Human oocytes have a delicate architecture but are freezable. Clinical efficiency remains low, but healthy children have been born, indicating that chromosomally normal embryos can originate from frozen oocytes. Freezing protocols are not yet optimal and it is now desirable to combine empirical and theoretical knowledge. (c) 2006 Elsevier Inc. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
