In pursuing the origin of informational polymers, we followed the assumption that their spontaneous formation could only have occurred: (i) if all the components were present at the same site and in the same reaction, and (ii) if the thermodynamics of the processes involved favored a polymerized over a monomeric state of the precursors. A plausible scenario satisfying both assumptions is provided. (C) 2009 Elsevier Masson SAS. All rights reserved.
From formamide to RNA: the roles of formamide and water in the evolution of chemical information / Raffaele, Saladino; Claudia, Crestini; Ciciriello, Fabiana; Pino, Samanta; Giovanna Maria, Costanzo; DI MAURO, Ernesto. - In: RESEARCH IN MICROBIOLOGY. - ISSN 0923-2508. - STAMPA. - 160:7(2009), pp. 441-448. [10.1016/j.resmic.2009.06.001]
From formamide to RNA: the roles of formamide and water in the evolution of chemical information
CICIRIELLO, FABIANA;PINO, SAMANTA;DI MAURO, Ernesto
2009
Abstract
In pursuing the origin of informational polymers, we followed the assumption that their spontaneous formation could only have occurred: (i) if all the components were present at the same site and in the same reaction, and (ii) if the thermodynamics of the processes involved favored a polymerized over a monomeric state of the precursors. A plausible scenario satisfying both assumptions is provided. (C) 2009 Elsevier Masson SAS. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
