A 71-year-old man with advanced left renal cell carcinoma (lymph node involvement and vena cava thrombus) was submitted to 6 months of neoadjuvant treatment with sorafenib before open radical nephrectomy. After sorafenib treatment and before surgery a new CT scan confirmed the presence of a 9.0 cm in diameter solid mass in the left kidney but a reduction in thrombus extension, limited to the left renal vein. At histological examination after radical nephrectomy, over 90% of the renal mass was substituted by necrotic tissue. Copyright © 2008 S. Karger AG.
Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy / DI SILVERIO, Franco; Sciarra, Alessandro; Parente, Ulderico; Alfarone, Andrea; VON HELAND, Magnus; Panebianco, Valeria; Passariello, Roberto. - In: UROLOGIA INTERNATIONALIS. - ISSN 0042-1138. - STAMPA. - 80:4(2008), pp. 451-453. [10.1159/000132708]
Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy
DI SILVERIO, Franco;SCIARRA, Alessandro;PARENTE, ULDERICO;ALFARONE, ANDREA;VON HELAND, Magnus;PANEBIANCO, VALERIA;PASSARIELLO, Roberto
2008
Abstract
A 71-year-old man with advanced left renal cell carcinoma (lymph node involvement and vena cava thrombus) was submitted to 6 months of neoadjuvant treatment with sorafenib before open radical nephrectomy. After sorafenib treatment and before surgery a new CT scan confirmed the presence of a 9.0 cm in diameter solid mass in the left kidney but a reduction in thrombus extension, limited to the left renal vein. At histological examination after radical nephrectomy, over 90% of the renal mass was substituted by necrotic tissue. Copyright © 2008 S. Karger AG.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
