Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor of amines, providing the corresponding 2-phenylseleno-3-amino succinates 2a and 2b in very high yields with complete regio- and good diastereoselectivity.
Selenium-directed conjugate addition of amines to 2-phenylseleno fumarate: regio- and diastereoselective synthesis of 2-phenylseleno-3-amino succinates / Bella, Marco; Donofrio, F; Margarita, R; Parlanti, L; Piancatelli, Giovanni; Mangoni, A.. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 38:(1997), pp. 7917-7918.
Selenium-directed conjugate addition of amines to 2-phenylseleno fumarate: regio- and diastereoselective synthesis of 2-phenylseleno-3-amino succinates
BELLA, Marco;PIANCATELLI, Giovanni;
1997
Abstract
Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor of amines, providing the corresponding 2-phenylseleno-3-amino succinates 2a and 2b in very high yields with complete regio- and good diastereoselectivity.File allegati a questo prodotto
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