The possibility of quantitatively analyzing some cholicacids by DSC is proposed using the heats of fusion. Some characteristic parameters of these analytical techniques have been evaluated for cholic, deoxycholic, chenodeoxycholic, ursodeoxycholic and lithocholic acids. The method has been applied to the analysis of two commercial drugs containing chenodeoxycholic and ursodeoxycholic acid, respectively. The results obtained are fully discussed.
Cholic acids determination from heats of fusion obtained using differential scanning calorimetry. Application to pharmaceutical products / U., Biader Ceipidor; Curini, Roberta; D'Ascenzo, Giuseppe; Tomassetti, Mauro. - In: THERMOCHIMICA ACTA. - ISSN 0040-6031. - STAMPA. - 46:3(1981), pp. 279-287. [10.1016/0040-6031(81)80326-7]
Cholic acids determination from heats of fusion obtained using differential scanning calorimetry. Application to pharmaceutical products
CURINI, Roberta;D'ASCENZO, Giuseppe;TOMASSETTI, Mauro
1981
Abstract
The possibility of quantitatively analyzing some cholicacids by DSC is proposed using the heats of fusion. Some characteristic parameters of these analytical techniques have been evaluated for cholic, deoxycholic, chenodeoxycholic, ursodeoxycholic and lithocholic acids. The method has been applied to the analysis of two commercial drugs containing chenodeoxycholic and ursodeoxycholic acid, respectively. The results obtained are fully discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
