The effect of growth in iron-excess or iron-limitation conditions on the invasiveness for HeLa cells of Escherichia coli HB101 carrying plasmid pRI203 which bears the invasion gene of Yersinia pseudotuberculosis was examined. Iron-limitation reduced adhesion and the number of organisms internalised by HeLa cells by about 100-fold. The reduced adhesion of iron-starved bacteria correlated with reduced hydrophobicity and the reduced invasiveness appeared to depend on the plasmid copy number, which was 3.5-fold less than in bacteria grown in iron excess.

The effect of iron on the invasiveness of Escherichia coli carrying the inv gene of Yersinia pseudotuberculosis / Conte, Maria Pia; Longhi, Catia; V., Buonfiglio; M., Polidoro; Seganti, Lucilla; Valenti, Piera. - In: JOURNAL OF MEDICAL MICROBIOLOGY. - ISSN 0022-2615. - 40:(1994), pp. 236-240. [10.1099/00222615-40-4-236]

The effect of iron on the invasiveness of Escherichia coli carrying the inv gene of Yersinia pseudotuberculosis.

CONTE, Maria Pia;LONGHI, Catia;SEGANTI, Lucilla;VALENTI, PIERA
1994

Abstract

The effect of growth in iron-excess or iron-limitation conditions on the invasiveness for HeLa cells of Escherichia coli HB101 carrying plasmid pRI203 which bears the invasion gene of Yersinia pseudotuberculosis was examined. Iron-limitation reduced adhesion and the number of organisms internalised by HeLa cells by about 100-fold. The reduced adhesion of iron-starved bacteria correlated with reduced hydrophobicity and the reduced invasiveness appeared to depend on the plasmid copy number, which was 3.5-fold less than in bacteria grown in iron excess.
1994
01 Pubblicazione su rivista::01a Articolo in rivista
The effect of iron on the invasiveness of Escherichia coli carrying the inv gene of Yersinia pseudotuberculosis / Conte, Maria Pia; Longhi, Catia; V., Buonfiglio; M., Polidoro; Seganti, Lucilla; Valenti, Piera. - In: JOURNAL OF MEDICAL MICROBIOLOGY. - ISSN 0022-2615. - 40:(1994), pp. 236-240. [10.1099/00222615-40-4-236]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/256689
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