The relative frequencies of X-ray-induced symmetrical and asymmetrical chromatid interchanges were analysed as a function of the cell cycle in somatic cells of Drosophila melanogaster. In exchanges between autosomes, during the S phase, a clear prevalence of asymmetrical rejoining was observed. Later, this prevalence became reduced as the cell approached mitosis. On the other hand, in the exchanges between X-chromosomes in the females there were no significant variations in the type of rejoining through the cell cycle, there being a slight but consistent preference for symmetrical rejoining. These data are discussed in relation to the hypothesis proposed by Olivieri et al. [12] on the organization of the chromosomal sub-units in the interphase nucleus.
X-ray induction of chromatid interchanges is somatic cells of Drosophila melanogaster: variations through the cell cycle of the pattern of rejoining / Pimpinelli, Sergio; D., Pignone; Gatti, Maurizio; Olivieri, Gregorio. - In: MUTATION RESEARCH. - ISSN 0027-5107. - STAMPA. - 35:1(1976), pp. 101-110.
X-ray induction of chromatid interchanges is somatic cells of Drosophila melanogaster: variations through the cell cycle of the pattern of rejoining.
PIMPINELLI, Sergio;GATTI, MAURIZIO;OLIVIERI, Gregorio
1976
Abstract
The relative frequencies of X-ray-induced symmetrical and asymmetrical chromatid interchanges were analysed as a function of the cell cycle in somatic cells of Drosophila melanogaster. In exchanges between autosomes, during the S phase, a clear prevalence of asymmetrical rejoining was observed. Later, this prevalence became reduced as the cell approached mitosis. On the other hand, in the exchanges between X-chromosomes in the females there were no significant variations in the type of rejoining through the cell cycle, there being a slight but consistent preference for symmetrical rejoining. These data are discussed in relation to the hypothesis proposed by Olivieri et al. [12] on the organization of the chromosomal sub-units in the interphase nucleus.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.